Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.
KMID : 1039620220120020110
Korean Journal of Family Practice
2022 Volume.12 No. 2 p.110 ~ p.115
Investigation of the Effect of Ultraviolet Light-Emitting Diodes Exposure Conditions on Serum Levels of 25-Hydroxyvitamin D in Female Adults with Vitamin D Insufficiency
Lee Shin-Hye

Kang Jae-Heon
Kim Cheol-Hwan
Sung Eun-Ju
Shin Ho-Cheol
Cho In-Young
Oh Su-Pa
Lim Jung-Sun
Kang Hyun-Joon
Yoon Hyun-Jung
Abstract
Background: To date, no research has been published on the effects of light-emitting diode (LED) devices emitting ultraviolet B (UVB) on serum 25-hydroxyvitamin D [25(OH)D] levels in humans. The objective of this study was to explore the efficacy and safety of UV-LED exposure by examining its effect on serum 25(OH)D levels in female adults with vitamin D insufficiency.

Methods: Among 13 female adults who visited the outpatient clinic of the Department of Family Medicine, Kangbuk Samsung Hospital, from June to July 2021, 9 female adults were included in the final analysis. Vitamin D insufficiency is defined as a serum 25(OH)D level of <30 ng/mL. The participants received UV-LED exposure three times per week for six weeks. Adverse reactions were assessed every two weeks after the first UV-LED exposure. The primary endpoint was the difference in serum 25(OH)D levels before and after six weeks of UV-LED exposure.

Results: We found a statistically significant increase in serum 25(OH)D levels after six weeks of UV-LED exposure (P<0.001). Moreover, no severe adverse reactions were observed.

Conclusion: Based on the results obtained, the UV-LED device could be a potentially safe and effective way to treat vitamin D insufficiency.
KEYWORD
Vitamin D, Females, Ultraviolet Light, Pilot Study
FullTexts / Linksout information
Listed journal information
ÇмúÁøÈïÀç´Ü(KCI) ´ëÇÑÀÇÇÐȸ ȸ¿ø