KMID : 1039620220120020110
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Korean Journal of Family Practice 2022 Volume.12 No. 2 p.110 ~ p.115
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Investigation of the Effect of Ultraviolet Light-Emitting Diodes Exposure Conditions on Serum Levels of 25-Hydroxyvitamin D in Female Adults with Vitamin D Insufficiency
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Lee Shin-Hye
Kang Jae-Heon Kim Cheol-Hwan Sung Eun-Ju Shin Ho-Cheol Cho In-Young Oh Su-Pa Lim Jung-Sun Kang Hyun-Joon Yoon Hyun-Jung
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Abstract
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Background: To date, no research has been published on the effects of light-emitting diode (LED) devices emitting ultraviolet B (UVB) on serum 25-hydroxyvitamin D [25(OH)D] levels in humans. The objective of this study was to explore the efficacy and safety of UV-LED exposure by examining its effect on serum 25(OH)D levels in female adults with vitamin D insufficiency.
Methods: Among 13 female adults who visited the outpatient clinic of the Department of Family Medicine, Kangbuk Samsung Hospital, from June to July 2021, 9 female adults were included in the final analysis. Vitamin D insufficiency is defined as a serum 25(OH)D level of <30 ng/mL. The participants received UV-LED exposure three times per week for six weeks. Adverse reactions were assessed every two weeks after the first UV-LED exposure. The primary endpoint was the difference in serum 25(OH)D levels before and after six weeks of UV-LED exposure.
Results: We found a statistically significant increase in serum 25(OH)D levels after six weeks of UV-LED exposure (P<0.001). Moreover, no severe adverse reactions were observed.
Conclusion: Based on the results obtained, the UV-LED device could be a potentially safe and effective way to treat vitamin D insufficiency.
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KEYWORD
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Vitamin D, Females, Ultraviolet Light, Pilot Study
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